Design, synthesis and in vitro validation of novel tools for lung cancer diagnosis and therapy

A better understanding of the mechanisms and processes that promote lung cancer is crucial to develop more efficient methods for early diagnosis and to implement more efficient therapeutic interventions. Based on the finding of new molecular targets and the design and development of novel drugs, we aim to inhibit cellular plasticity/stemness as a potential lung cancer therapy. In addition, we are developing new cargo-delivery systems based on nanoparticles that are activated specifically in damaged and/or premalignant cells.